Article
Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
Pharmacogenomics - 1 Jul 2011
Nyberg Fredrik, Barratt Bryan J, Mushiroda Taisei, Takahashi Atsushi, Jawaid Ansar, Hada Shuji, Umemura Takaaki, Fukuoka Masahiro, Nakata Koichiro, Ohe Yuichiro, Kato Harubumi, Kudoh Shoji, March Ruth, Nakamura Yusuke, Kamatani Naoyuki
Abstract excerpt
AIM: To investigate potential relationships between SNPs and acute interstitial lung disease (ILD) events in Japanese non-small-cell lung cancer patients receiving gefitinib. MATERIALS & METHODS: Japanese non-small-cell lung cancer patients treated with gefitinib from a prospective pharmacoepidemiological cohort with a nested case-control study component ('CCS'; 52 ILD cases, 139 controls) and a retrospective...
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