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Article

Advanced age impairs cardioprotective function of mesenchymal stem cell transplantation from patients to myocardially infarcted rats.

Cardiology - 1 Jan 2014

Liu Yu, Liu Tao, Han Jinsong, Yang Zhonglu, Xue Xiaodong, Jiang Hui, Wang Huishan

Abstract excerpt

OBJECTIVES: Mesenchymal stem cells (MSCs) have limited clinical therapeutic effects in older myocardial infarction (MI) patients. Thus, whether younger MSCs might confer greater protection is worth investigating. METHODS: Human MSCs (hMSCs) were isolated before coronary artery bypass graft surgery and growth characteristics of hMSCs at passage 3 were observed. Vascular endothelial growth factor (VEGF) and Bcl-2...

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Source

Identifiers

PMID: 24818643
DOI: 10.1159/000360393

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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