Article
Neutrophil elastase gene polymorphisms: modulators of response to therapy in childhood bronchiectasis?
Lung - 1 Aug 2014
Nikolic Aleksandra, Milosevic Katarina, Boskovic Srdjan, Nestorovic Branimir
Abstract excerpt
BACKGROUND: The aim of this study was to investigate polymorphisms in the promoter region of the neutrophil elastase (ELANE) gene as potential modulators of the therapeutic response in children with idiopathic bronchiectasis. METHODS: The study included 48 children between 5 and 17 years old who were diagnosed with idiopathic bronchiectasis based on high-resolution computed tomography of the thorax. In all...
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