Article
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma.
International journal of molecular sciences - 26 Jul 2024
Rojo-Tolosa Susana, Sánchez-Martínez José Antonio, Caballero-Vázquez Alberto, Pineda-Lancheros Laura Elena, González-Gutiérrez María Victoria, Pérez-Ramírez Cristina, Jiménez-Morales Alberto, Morales-García Concepción
Abstract excerpt
The most promising treatment options for severe uncontrolled asthma (SUA) have emerged in recent years with the development of monoclonal antibodies for blocking selective targets responsible for the underlying inflammation, such as mepolizumab and benralizumab. However, there is variability in treatment response that is not fully controlled. The variability of the response to mepolizumab and benralizumab could...
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