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Article

Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells.

PloS one - 1 Jan 2014

Shaw-Hallgren Gina, Chmielarska Masoumi Katarzyna, Zarrizi Reihaneh, Hellman Ulf, Karlsson Per, Helou Khalil, Massoumi Ramin

Abstract excerpt

Nemo-like kinase (NLK), a proline-directed serine/threonine kinase regulated by phosphorylation, can be localized in the cytosol or in the nucleus. Whether the localization of NLK can affect cell survival or cell apoptosis is yet to be disclosed. In the present study we found that NLK was mainly localized in the nuclei of breast cancer cells, in contrast to a cytosolic localization in non-cancerous breast...

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Share to Antineoplastic Agents, Phytogenic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24816797
DOI: 10.1371/journal.pone.0096506
PMCID: PMC4015990

Genes

NLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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