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Article

The evaluation of endothelin 1 (EDN1) and endothelin receptor type A (EDNRA) gene polymorphisms in Hashimoto's thyroiditis.

International immunopharmacology - 1 Jul 2014

Aydin A Fatih, Vural Pervin, Oruç Çoşkun Umut, Doğru-Abbasoğlu Semra, Özderya Ayşenur, Karadağ Berrin, Uysal Müjdat

Abstract excerpt

PURPOSE: Endothelin1 (EDN1) is well established marker of inflammation. The functions of EDN1 are mediated mainly by endothelin receptors type A (EDNRA). The etiopathogenesis of Hashimoto's thyroiditis (HT) remains still elusive although the role of chronic inflammation and subsequent endothelial dysfunction has been established. This study examined firstly the possible association of EDN1 (G5665Tand T-1370G) and...

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Source

Identifiers

PMID: 24815860
DOI: 10.1016/j.intimp.2014.04.023

Genes

EDNRA
EDN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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