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Article

Polymorphisms in TSHR and IL1RN genes and the risk and prognosis of Hashimoto's thyroiditis.

Autoimmunity - 1 Mar 2014

Zaaber Ines, Mestiri Souhir, Marmouch Hela, Mahjoub Silvia, Abid Nabil, Hassine Mohsen, Bel Hadj Jrad-Tensaout Besma, Said Khaled

Abstract excerpt

Hashimoto's thyroiditis (HT) is a complex genetic autoimmune thyroid disease (AITD). Thyroid-stimulating hormone receptor (TSHR) is considered as candidate gene in AITD. IL1RN gene is involved in the pathogenesis of a number of autoimmune diseases. These findings prompted us to investigate the association of TSHR and IL1RN genes polymorphism with the risk and the prognosis of HT in Tunisia. A total of 249 healthy...

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Source

Identifiers

PMID: 24328419
DOI: 10.3109/08916934.2013.866101

Genes

TSHR

Variants

Provenance

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