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Article

IL18 production and IL18 promoter polymorphisms correlate with mortality in ICU patients.

In vivo (Athens, Greece) - 1 Jan 2000

Yamada Taihei, Aoyama-Ishikawa Michiko, Yamashita Hayato, Fujiwara Mayu, Usami Makoto, Ueda Takahiro, Terashima Mariko, Kohama Keisuke, Nakao Atsunori, Kotani Joji

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms in the promoter of interleukin (IL)-18 (-607C/A and -137G/C) may affect the clinical course of inflammatory diseases. This study examined the relationship between the plasma IL18 levels, IL18 promoter polymorphism, and outcomes in the intensive care unit (ICU) setting. PATIENTS AND METHODS: Plasma IL18 levels, IL18 promoter genotype, clinical variables, including APACHE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24815843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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