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Article

Interleukin-18 gene promoter polymorphisms and the risk of esophageal squamous cell carcinoma.

Acta oncologica (Stockholm, Sweden) - 1 Jan 2007

Wei Ye-Sheng, Lan Yan, Liu Yun-Guang, Tang Hui, Tang Ren-Guang, Wang Jian-Chu

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is multifactorial, and the genetic background may be a crucial etiologic factor. Interleukin-18 (IL-18) is a multifunctional cytokine that induces interferon (IFN)-gamma secretion and plays an important role in antitumor immunity. Variations in the DNA sequence in the IL-18 gene promoter may lead to altered IL-18 production and/or activity, and so this can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17851835
DOI: 10.1080/02841860701373595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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