Article
DNA methylation profiling of well-differentiated thyroid cancer uncovers markers of recurrence free survival.
International journal of cancer - 1 Aug 2014
Mancikova Veronika, Buj Raquel, Castelblanco Esmeralda, Inglada-Pérez Lucía, Diez Anna, de Cubas Aguirre A, Curras-Freixes Maria, Maravall Francisco Xavier, Mauricio Didac, Matias-Guiu Xavier, Puig-Domingo Manel, Capel Ismael, Bella María Rosa, Lerma Enrique, Castella Eva, Reverter Jordi Lluis, Peinado Miguel Ángel, Jorda Mireia, Robledo Mercedes
Abstract excerpt
Thyroid cancer is a heterogeneous disease with several subtypes characterized by cytological, histological and genetic alterations, but the involvement of epigenetics is not well understood. Here, we investigated the role of aberrant DNA methylation in the development of well-differentiated thyroid tumors. We performed genome-wide DNA methylation profiling in the largest well-differentiated thyroid tumor series...
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