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Article

Pharmacoepigenetics of depression: no major influence of MAO-A DNA methylation on treatment response.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2015

Domschke Katharina, Tidow Nicola, Schwarte Kathrin, Ziegler Christiane, Lesch Klaus-Peter, Deckert Jürgen, Arolt Volker, Zwanzger Peter, Baune Bernhard T

Abstract excerpt

The monoamine oxidase A (MAO-A) gene has been suggested to be involved in the pathogenesis as well as the pharmacological treatment of major depressive disorder. In the present analysis, for the first time a pharmacoepigenetic approach was applied investigating the influence of DNA methylation patterns in the MAO-A regulatory and exon1/intron1 region on antidepressant treatment response. 94 patients of Caucasian...

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PMID: 24809685
DOI: 10.1007/s00702-014-1227-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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