Article
Altered sequence of the ETS1 transcription factor may predispose to rheumatoid arthritis susceptibility.
Scandinavian journal of rheumatology - 1 Jan 2013
Chatzikyriakidou A, Voulgari P V, Georgiou I, Drosos A A
Abstract excerpt
OBJECTIVE: ETS1 belongs to the ETS family of transcription factors that regulate the expression of various immune-related genes. The aim of this study was to identify whether the ETS1 single nucleotide polymorphism (SNP) rs11221332, described in Caucasian subjects, plays a role in rheumatoid arthritis (RA) susceptibility. METHODS: We genotyped this polymorphism in 136 unrelated patients with RA and 147 healthy...
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