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Article

Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.

Journal of biochemistry - 1 Oct 2003

Noguchi Akio, Yano Masayasu, Ohshima Yasuhiro, Hemmi Hisashi, Inohara-Ochiai Misa, Okada Maki, Min Kyong-Son, Nakayama Toru, Nishino Tokuzo

Abstract excerpt

The alpha-glucosidase of Bacillus sp. strain SAM1606 is a member of glycosyl hydrolase family 13, and shows an extraordinarily broad substrate specificity and is one of very few alpha-glucosidases that can efficiently hydrolyze the alpha-1,1-glucosidic linkage of alpha,alpha'-trehalose (trehalose). Phylogenetic analysis of family-13 enzymes suggests that SAM1606 alpha-glucosidase may be evolutionally derived from...

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PMID: 14607981
DOI: 10.1093/jb/mvg172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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