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Article

Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1.

mBio - 6 May 2014

Shi Shuobo, Chen Yun, Siewers Verena, Nielsen Jens

Abstract excerpt

ABSTRACT Acetyl coenzyme A (acetyl-CoA) carboxylase (ACCase) plays a central role in carbon metabolism and has been the site of action for the development of therapeutics or herbicides, as its product, malonyl-CoA, is a precursor for production of fatty acids and other compounds. Control of Acc1 activity in the yeast Saccharomyces cerevisiae occurs mainly at two levels, i.e., regulation of transcription and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24803522
DOI: 10.1128/mBio.01130-14
PMCID: PMC4010835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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