Article
Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population.
Human immunology - 1 Feb 2008
Lemos Manuel C, Fagulha Ana, Coutinho Eduarda, Gomes Leonor, Bastos Margarida, Barros Luisa, Carrilho Francisco, Geraldes Elizabete, Regateiro Fernando J, Carvalheiro Manuela
Abstract excerpt
The vitamin D receptor (VDR) gene is a candidate gene for susceptibility to autoimmune disorders. Association studies of VDR polymorphisms and risk of type 1 diabetes often produced conflicting results in different ethnic backgrounds. The aim of this study was to test for association between common VDR polymorphisms and the genetic susceptibility to type 1 diabetes in the Portuguese population. We genotyped 207...
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