Article
Associations of vitamin D receptor gene polymorphisms FokI and BsmI with susceptibility to rheumatoid arthritis and Behçet's disease in Tunisians.
Joint bone spine - 1 Mar 2012
Karray Emna Fakhfakh, Ben Dhifallah Imen, Ben Abdelghani Kawther, Ben Ghorbel Imed, Khanfir Monia, Houman Habib, Hamzaoui Kamel, Zakraoui Leith
Abstract excerpt
OBJECTIVES: Reports of immunomodulating effects of vitamin D suggest a need for examining allele and genotype frequencies of the vitamin D nuclear receptor gene (VDR) in patients with autoimmune diseases. T-helper-1 (Th1) counts in peripheral blood are increased in both rheumatoid arthritis (RA) and Behçet's disease (BD). We studied VDR polymorphisms in patients with these two diseases in Tunisia. METHODS: In 108...
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