Article
Deletion of the MGMT gene in familial melanoma.
Genes, chromosomes & cancer - 1 Aug 2014
Appelqvist Frida, Yhr Maria, Erlandson Anna, Martinsson Tommy, Enerbäck Charlotta
Abstract excerpt
The DNA repair gene MGMT (O-6-methylguanine-DNA methyltransferase) is important for maintaining normal cell physiology and genomic stability. Alterations in MGMT play a critical role in the development of several types of cancer, including glioblastoma, lung cancer, and colorectal cancer. The pur...
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