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Article

Signal transducer and activator of transcription and the risk of rheumatoid arthritis and thyroid autoimmune disorders.

Clinical and experimental rheumatology - 1 Jan 2000

Ben Hamad M, Cornelis F, Mbarek H, Chabchoub G, Marzouk S, Bahloul Z, Rebai A, Fakhfakh F, Ayadi H, Petit-Teixeira E, Maalej A

Abstract excerpt

OBJECTIVES: The signal transducer and activator of transcription 4 (STAT4) gene localised on chromosome 2q32.2-q32.3 is known to be essential for mediating responses to interleukin 12 in lymphocytes and regulating the differentiation of T helper cells. The aim of this study was to investigate the role of the STAT4 gene in susceptibility to rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs) in...

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Source

Identifiers

PMID: 21418779

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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