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Article

Early-life estrogens and prostate cancer in an animal model

9 Nov 2010

Abstract excerpt

While early-life estrogens are thought to play a physiologic role in prostate gland development, inappropriate estrogenic exposures either in dose, type or temporally can reprogram the prostate gland and increase susceptibility to abnormal prostate growth with aging including carcinogenesis. This review discusses the evidence for developmental estrogenic reprogramming that leads to adult prostate disease in a rat...

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PMID: 24795802
DOI: 10.1017/s2040174410000577

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