Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endocrine disruptors and epigenetic transgenerational disease etiology.

Pediatric research - 1 May 2007

Skinner Michael K

Abstract excerpt

Exposure to an environmental factor (e.g. endocrine disruptor) during embryonic gonadal sex determination appears to be epigenetically reprogram the male germ-line and subsequently promote transgenerational adult-onset disease. Disease phenotypes resulting from this epigenetic phenomenon include testis abnormalities, prostate disease, kidney disease, tumor development, and immune abnormalities. The epigenetic...

Topics

Adult
Animals
Disease
Endocrine Disruptors
Environmental Pollutants
Epigenesis, Genetic
Female
Genomic Imprinting
Germ Cells
Humans
Male
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Prenatal Exposure Delayed Effects

Sex Determination Processes

Sex Differentiation

Source

Open in PubMed Open full text

Identifiers

PMID: 17413841
DOI: 10.1203/pdr.0b013e3180457671
PMCID: PMC5940327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endocrine disruptors and epigenetic transgenerational disease etiology.PMID 17413841Read ↗

Epigenetic programming of the germ line: effects of endocrine disruptors on the development of transgenerational diseaseSemantic proximity Read ↗

Epigenetic transgenerational effects of endocrine disruptors on male reproduction.Semantic proximity Read ↗

Environmental Transgenerational Epigenetics: Effects on Fertility and Offspring Health.Semantic proximity Read ↗

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease.Semantic proximity Read ↗

Impact of Endocrine Disruptors upon Non-Genetic InheritanceSemantic proximity Read ↗

Endocrine disruptors, gene deregulation and male germ cell tumorsSemantic proximity Read ↗

Epigenetics, Evolution, Endocrine Disruption, Health, and DiseaseSemantic proximity Read ↗

The epigenetic impacts of endocrine disruptors on female reproduction across generations†Semantic proximity Read ↗

Environmentally Induced Epigenetic Transgenerational Inheritance of Reproductive Disease1Semantic proximity Read ↗

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral ExposuresSemantic proximity Read ↗

Multigenerational and transgenerational effects of endocrine disrupting chemicals: A role for altered epigenetic regulation?Semantic proximity Read ↗

Endocrine disruptors in 2015: Epigenetic transgenerational inheritance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.