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Article

Endocrine disruptors and epigenetic transgenerational disease etiology.

Pediatric research - 1 May 2007

Skinner Michael K

Abstract excerpt

Exposure to an environmental factor (e.g. endocrine disruptor) during embryonic gonadal sex determination appears to be epigenetically reprogram the male germ-line and subsequently promote transgenerational adult-onset disease. Disease phenotypes resulting from this epigenetic phenomenon include testis abnormalities, prostate disease, kidney disease, tumor development, and immune abnormalities. The epigenetic...

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Identifiers

PMID: 17413841
DOI: 10.1203/pdr.0b013e3180457671
PMCID: PMC5940327

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Source receipt: pubmed, retrieved 7 Sept 2026.

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