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Article

DNA Methylation as a Dynamic Regulator of Development and Disease Processes: Spotlight on the Prostate

1 Jun 2015

Abstract excerpt

Prostate development, benign hyperplasia and cancer involve androgen and growth factor signaling as well as stromal-epithelial interactions. We review how DNA methylation influences these and related processes in other organ systems such as how proliferation is restricted to specific cell populations during defined temporal windows, how androgens elicit their actions and how cells establish, maintain and remodel...

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Identifiers

PMID: 26077429
DOI: 10.2217/epi.15.8

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