Article
CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Mar 2021
Ashraf Sairish, Rasool Shayaq Ul Abeer, Nabi Mudasar, Ganie Mohd Ashraf, Jabeen Farhat, Rashid Fouzia, Amin Shajrul
Abstract excerpt
OBJECTIVE: Polycystic ovarian syndrome is a complex reproductive as well as endocrinological disorder characterized by anovulatory dysfunction, androgen excess and polycystic ovarian morphology. Hyperandrogenism is regarded as a cardinal feature of the disease. It is believed that the excess androgens are produced due to abnormality in steroid biosynthesis pathway wherein cytochrome P450, 17α-hydroxylase (CYP17)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
