Article
An open-source analytical platform for analysis of C. elegans swimming-induced paralysis.
Journal of neuroscience methods - 30 Jul 2014
Hardaway J Andrew, Wang Jing, Fleming Paul A, Fleming Katherine A, Whitaker Sarah M, Nackenoff Alex, Snarrenberg Chelsea L, Hardie Shannon L, Zhang Bing, Blakely Randy D
Abstract excerpt
BACKGROUND: The nematode Caenhorhabditis elegans offers great power for the identification and characterization of genes that regulate behavior. In support of this effort, analytical methods are required that provide dimensional analyses of subcomponents of behavior. Previously, we demonstrated that loss of the presynaptic dopamine (DA) transporter, dat-1, evokes DA-dependent Swimming-Induced Paralysis (Swip)...
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