Article
Quantitative X-ray microradiography for high-throughput phenotyping of osteoarthritis in mice.
Osteoarthritis and cartilage - 1 Oct 2014
Waung J A, Maynard S A, Gopal S, Gogakos A, Logan J G, Williams G R, Bassett J H D
Abstract excerpt
OBJECTIVE: To investigate and validate digital X-ray microradiography as a novel, high-throughput and cost-effective screening approach to identify abnormal joint phenotypes in mice. METHOD: Digital X-ray microradiography was used to quantify the subchondral bone mineral content (BMC) in the medial tibial plateau. Accuracy and reproducibility of the method were determined in 22 samples from...
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