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Article

Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Apr 2014

Montgomery Therese R, Steinkellner Thomas, Sucic Sonja, Koban Florian, Schüchner Stefan, Ogris Egon, Sitte Harald H, Freissmuth Michael

Abstract excerpt

Export of the serotonin transporter (SERT) from the endoplasmic reticulum (ER) is mediated by the SEC24C isoform of the coatomer protein-II complex. SERT must enter the axonal compartment and reach the presynaptic specialization to perform its function, i.e., the inward transport of serotonin. Refilling of vesicles is contingent on the operation of an efficient relay between SERT and the vesicular monoamine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24790205
DOI: 10.1523/JNEUROSCI.2991-13.2014
PMCID: PMC4497811

Genes

SEC24C
SEC24D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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