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Article

Biphosphonates-associated osteonecrosis of the jaw: the role of gene-environment interaction.

Journal of preventive medicine and hygiene - 1 Sept 2013

Izzotti A, Menini M, Pulliero A, Dini G, Cartiglia C, Pera P, Baldi D

Abstract excerpt

Biphosphonate (BPN) are widely used in clinics to treat metastatic cancer and osteoporosis thus representing a problem not only for patients but also for workers involved in their preparation and administration. A similar exposure occurred years ago in match-making workers undergoing bone alterations similar to those consequent to BPN exposure. Osteonecrosis of the jaw (ONJ) is a main adverse effect related to...

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PMID: 24783891
PMCID: PMC4718369

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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