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EgoNet: identification of human disease ego-network modules

28 Apr 2014

Abstract excerpt

BACKGROUND: Mining novel biomarkers from gene expression profiles for accurate disease classification is challenging due to small sample size and high noise in gene expression measurements. Several studies have proposed integrated analyses of microarray data and protein-protein interaction (PPI) networks to find diagnostic subnetwork markers. However, the neighborhood relationship among network member genes has...

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PMID: 24773628
DOI: 10.1186/1471-2164-15-314

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