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Article

Five-year monitoring of considerable changes in tyrosine phosphorylation motifs of the Helicobacter pylori cagA gene in Iran.

Journal of applied genetics - 1 Aug 2014

Kargar Mohammad, Ghorbani-Dalini Sadegh, Doosti Abbas, Najafi Akram

Abstract excerpt

CagA is a major virulence factor of Helicobacter pylori involved in host cell modulation. The C-terminal part of CagA containing the EPIYA motifs is highly variable and is important for the biological activity of the protein. The aim of this study was consideration of the changes in cagA tyrosine phosphorylation motifs (TPMs) of H. pylori. A set of 302 H. pylori DNA samples from the Iranian population from 2006...

Topics

3' Untranslated Regions
Amino Acid Motifs
Antigens, Bacterial
Bacterial Proteins
DNA, Bacterial
Genetic Variation
Helicobacter Infections
Helicobacter pylori
Humans
Phosphorylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Time Factors

Tyrosine

Source

Identifiers

PMID: 24771298
DOI: 10.1007/s13353-014-0209-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24771298-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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