Article
Monocyte-derived dendritic cells from HLA-matched allogeneic donors showed a greater ability to induce leukemic cell-specific T cells in comparison to leukemic cell-derived dendritic cells or monocyte-derived dendritic cells from AML patients.
Leukemia research - 1 Nov 2008
Lee Je-Jung, Choi Bo-Hwa, Kang Hyun-Kyu, Kim Sang-Ki, Nam Jong-Hee, Yang Deok-Hwan, Kim Yeo-Kyeoung, Kim Hyeoung-Joon, Chung Ik-Joo
Abstract excerpt
We investigated the usefulness of allogeneic monocyte-derived dendritic cells (allogeneic mDCs) pulsed with leukemic lysates in acute myeloid leukemia (AML). Allogeneic mDCs showed higher expressions of several molecules (HLA-DR, CD80, CD83 or CD86), higher production of IL-12 and higher capacity...
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