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Article

Epigenetics in lupus

1 Jan 2011

Abstract excerpt

Accumulating epidemiological, clinical, and experimental evidence supports the conclusion of a critical role of epigenetic factors in immune programming. This understanding provides the basis for elucidating how the intricate interactions of the genome, epigenome, and transcriptome shape immune responses and maintain immune tolerance to self-antigens. Deciphering the precise contribution of epigenetic factors to...

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PMID: 21251010
DOI: 10.1111/j.1749-6632.2010.05831.x

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