Article
Analysis of HLA-G gene polymorphism and protein expression in invasive breast ductal carcinoma.
Human immunology - 1 Jul 2014
Ramos Caroline Steglich, Gonçalves Andréia Souza, Marinho Larissa Cardoso, Gomes Avelino Melissa Ameloti, Saddi Vera Aparecida, Lopes Aryanne Cristina, Simões Renata Toscano, Wastowski Isabela Jubé
Abstract excerpt
The human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule predominantly expressed in trophoblastic placental cells to protect the fetus during pregnancy. However, evidence has shown that this molecule may be implicated in the immune escape mechanism of tumor cells. Thus, the aim of this study was to evaluate the frequency of 14-bp insertion/deletion HLA-G polymorphism, as well as the...
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