Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Doublecortin may play a role in defining chondrocyte phenotype.

International journal of molecular sciences - 22 Apr 2014

Ge Dongxia, Zhang Qing-Song, Zabaleta Jovanny, Zhang Qiuyang, Liu Sen, Reiser Brendan, Bunnell Bruce A, Braun Stephen E, O'Brien Michael J, Savoie Felix H, You Zongbing

Abstract excerpt

Embryonic development of articular cartilage has not been well understood and the role of doublecortin (DCX) in determination of chondrocyte phenotype is unknown. Here, we use a DCX promoter-driven eGFP reporter mouse model to study the dynamic gene expression profiles in mouse embryonic handplates at E12.5 to E13.5 when the condensed mesenchymal cells differentiate into either endochondral chondrocytes or joint...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chondrocytes
Share to Doublecortin Domain Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Doublecortin Protein

Share to Embryo, Mammalian

Share to Embryonic Development

Share to Mesenchymal Stem Cells

Share to Microtubule-Associated Proteins

Share to Neuropeptides

Source

Open in PubMed Open full text

Identifiers

PMID: 24758934
DOI: 10.3390/ijms15046941
PMCID: PMC4013671

Genes

DCX
GDF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Doublecortin may play a role in defining chondrocyte phenotype.PMID 24758934Read ↗

Global comparative transcriptome analysis of cartilage formation in vivoSemantic proximity Read ↗

Identification of a novel human doublecortin-domain-containing gene (DCDC1) expressed mainly in testis.Semantic proximity Read ↗

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritisSemantic proximity Read ↗

The study of differential expressions of MCPH and Seckel syndrome genes and their paraloguesSemantic proximity Read ↗

Deep phenotyping of ATDC5-derived in vitro cartilage organoidsSemantic proximity Read ↗

Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice.Semantic proximity Read ↗

Impaired Intervertebral Disc Development and Premature Disc Degeneration in Mice With Notochord‐Specific Deletion of CCN2Semantic proximity Read ↗

Podocalyxin and ciliary neurotrophic factor receptor are novel components of the surfaceome of chondrogenic cellsSemantic proximity Read ↗

Developmental regulation of biglycan expression in muscle and tendonSemantic proximity Read ↗

Doublecortin is required in mice for lamination of the hippocampus but not the neocortex.Semantic proximity Read ↗

Type II Collagen-Positive Embryonic Progenitors are the Major Contributors to Spine and Intervertebral Disc Development and RepairSemantic proximity Read ↗

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.