Article

The study of differential expressions of MCPH and Seckel syndrome genes and their paralogues

2025-05-27

Abstract excerpt

Seckel syndrome and MCPH are single-gene neurodevelopmental disorders, with or without dwarfism. These genes are parts of essential cellular pathways but are regulated differently in both forms of microcephaly. These genes have diverged from single ancestral genes in to related but different gene paralogues during evolution. It is suggested that the paralogues might be redundant in other body organs and might resc...

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Literature Corpus work: 8210a207-36cb-5bda-ab39-59b44055c827
DOI: 10.1101/2025.05.21.655339

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