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Article

The evolution of connectivity in metabolic networks.

PLoS biology - 1 Jul 2005

Pfeiffer Thomas, Soyer Orkun S, Bonhoeffer Sebastian

Abstract excerpt

Processes in living cells are the result of interactions between biochemical compounds in highly complex biochemical networks. It is a major challenge in biology to understand causes and consequences of the specific design of these networks. A characteristic design feature of metabolic networks is the presence of hub metabolites such as ATP or NADH that are involved in a high number of reactions. To study the...

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PMID: 16000019
DOI: 10.1371/journal.pbio.0030228
PMCID: PMC1157096

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