Article
Impact of iron deficiency on hemoglobin A2% in obligate β-thalassemia heterozygotes.
International journal of laboratory hematology - 1 Feb 2015
Sharma P, Das R, Trehan A, Bansal D, Chhabra S, Kaur J, Marwaha R K, Varma N, Garewal G
Abstract excerpt
INTRODUCTION: The potential impact of concomitant iron deficiency on hemoglobin A2 (HbA2)-based identification of β-thalassemia trait (βTT) is a worrisome issue for screening laboratories. This is especially true for resource-constrained settings where iron deficiency is widespread and molecular confirmatory tests for borderline low HbA2 values may be unavailable. METHODS: Obligate βTT carrier individuals...
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