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Article

Association of a MiR-499 SNP and risk of congenital heart disease in a Chinese population.

Cellular and molecular biology (Noisy-le-Grand, France) - 30 Jul 2018

Guo Rui, Feng Zhiyu, Yang Yanliang, Xu Huihui, Zhang Jian, Guo Kai, Bi Yanwen

Abstract excerpt

MicroRNAs (miRNAs) play an important role in heart development. Single nucleotide polymorphisms (SNPs) in miRNAs have been shown to associate with congenital heart disease (CHD). Methionine synthase (MTR), a key enzyme of folate metabolism, is involved in the early embryonic development. In this study, we aimed to test whether MTR is a direct target of miR-499, and to estimate the associations between miR-499...

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Source

Identifiers

PMID: 30084801

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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