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Potential risk assessment of miR-143 gene polymorphisms rs41291957 and rs353292 in colorectal cancer.

Cellular and molecular biology (Noisy-le-Grand, France) - 31 Oct 2020

Ahmed Mehvish Naseer, Mansoor Qaisar, Baig Ruqia Mehmood, Tahir Tehreem, Abbasi Samina Asghar

Abstract excerpt

Colorectal cancer is a life-threatening and therapeutically challenging disease. Increasingly it is being deciphered that genetic and epigenetic mutations play a central role in cancer onset and progression. Excitingly, discovery of non-coding RNAs is considered to be a milestone in molecular oncology and emerging evidence is deepening our understanding about pivotal role of miRNAs in carcinogenesis. miR-143 has...

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PMID: 33287937

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