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Article

NOS3 genotype-dependent correlation between blood pressure and physical activity.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2003

Kimura Tomomi, Yokoyama Tetsuji, Matsumura Yasuhiro, Yoshiike Nobuo, Date Chigusa, Muramatsu Masaaki, Tanaka Heizo

Abstract excerpt

Endothelium-dependent vasorelaxation plays an important role in reduction of blood pressure and is mediated through release of nitric oxide (NO), which is generated by constitutively expressed endothelial nitric oxide synthase (NOS3). Exercise also augments NO release and has been recommended for primary prevention and improvement of hypertension, but individual responses are highly variable. We therefore...

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Source

Identifiers

PMID: 12574107
DOI: 10.1161/01.hyp.0000051500.02578.6d

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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