Article
Combined exercise training decreases blood pressure in OLDER women with NOS3 polymorphism providing changes in differentially methylated regions (DMRs).
Epigenetics - 1 Dec 2024
da Silva Rodrigues Guilherme, Yumi Noronha Natalia, Ribeiro de Lima João Gabriel, Harumi Yonehara Noma Isabela, Crystine da Silva Sobrinho Andressa, Maria Diani Luísa, Pinto Ana P, Pereira Rodrigues Karine, Augusta de Souza Pinhel Marcela, Barbosa Nonino Carla, Moriguchi Watanabe Lígia, Roberto Bueno Júnior Carlos
Abstract excerpt
The mechanisms by which the ageing process is associated to an unhealthy lifestyle and how they play an essential role in the aetiology of systemic arterial hypertension have not yet been completely elucidated. Our objective is to investigate the influence of NOS3 polymorphisms [-786T > C and (Glu298Asp)] on systolic blood pressure (SBP) and diastolic blood pressure (DBP) response, differentially methylated...
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