Article
Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma.
Nature cell biology - 1 May 2014
Shin Kunyoo, Lim Agnes, Odegaard Justin I, Honeycutt Jared D, Kawano Sally, Hsieh Michael H, Beachy Philip A
Abstract excerpt
Understanding how malignancies arise within normal tissues requires identification of the cancer cell of origin and knowledge of the cellular and tissue dynamics of tumour progression. Here we examine bladder cancer in a chemical carcinogenesis model that mimics muscle-invasive human bladder canc...
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