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Article

Differentiation of a Highly Tumorigenic Basal Cell Compartment in Urothelial Carcinoma

9 Apr 2009

Abstract excerpt

Highly tumorigenic cancer cell (HTC) populations have been identified for a variety of solid tumors and assigned stem cell properties. Strategies for identifying HTCs in solid tumors have been primarily empirical rather than rational, particularly in epithelial tumors, which are responsible for 80% of cancer deaths. We report evidence for a spatially restricted bladder epithelial (urothelial) differentiation...

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PMID: 19544456
DOI: 10.1002/stem.92

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