Article
TGF-β/VEGF-A Genetic Variants Interplay in Genetic Susceptibility to Non-Melanocytic Skin Cancer.
Genes - 13 Jul 2022
Scola Letizia, Bongiorno Maria Rita, Forte Giusi Irma, Aiello Anna, Accardi Giulia, Scrimali Chiara, Spina Rossella, Lio Domenico, Candore Giuseppina
Abstract excerpt
Differential genetically determined expression of transforming growth factor-β (TGF-β pathway and of vascular endothelial growth factor-A (VEGF-A) might modulate the molecular "milieu" involved in the etio-pathogenesis of non-melanoma skin cancer (NMSC). We have evaluated the frequency of some functionally relevant SNPs of TGF-β and VEGF-A genes in 70 NMSC patients and 161 healthy controls, typed for TGF-β1...
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