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Article

Multidrug resistance protein-1 expression, function and polymorphisms in patients with rheumatoid arthritis not responding to methotrexate.

International journal of rheumatic diseases - 1 Nov 2014

Prasad Shiva, Tripathi Deepak, Rai Mohit K, Aggarwal Suraksha, Mittal Balraj, Agarwal Vikas

Abstract excerpt

OBJECTIVE: To study the expression, function and polymorphism of MDR-1 protein on the peripheral blood lymphocytes in patients with RA following treatment with MTX and its relationship with response to therapy. METHODS: RA patients naïve to MTX/DMARD- and glucocorticoid were enrolled. Expression and function of MDR-1 was carried out by flow cytometry at baseline and after 4 months of therapy. MDR-1 expression was...

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Share to Antirheumatic Agents
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Genotyping Techniques

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Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 24734954
DOI: 10.1111/1756-185X.12362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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