Article
CaMac1, a Candida albicans copper ion-sensing transcription factor, promotes filamentous and invasive growth in Saccharomyces cerevisiae.
Acta biochimica et biophysica Sinica - 1 Mar 2006
Huang Guang-Hua, Nie Xin-Yi, Chen Jiang-Ye
Abstract excerpt
Molecular mechanisms of morphogenesis share many common components between Candida albicans and Saccharomyces cerevisiae. The Kss1-associated MAPK cascade and the cAMP/PKA pathway are two important signal transduction pathways that control morphogenesis in S. cerevisiae. A C. albicans copper ion-sensing transcription factor gene, CaMAC1, was cloned from C. albicans SC5314. Ectopic expression of CaMAC1 in S....
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