Article
Identification of a novel heterozygous germline RAD52 missense mutation in a patient with gallbladder carcinoma: A case report.
Medicine - 14 May 2021
Zhao Wenhu, Dai Yongjiu, Yue Lei, Gu Jian, Meng Erhong, Wang Dongliang, Liu Siyao, Han Xinyin, Wang Xintong, Li Guojun, Dai Xinzheng
Abstract excerpt
RATIONALE: Gallbladder carcinoma is a malignant biliary tract tumor which is characterized by poor prognosis. Recent advances in genomic medicine have identified a few novel germline mutations that contribute to the increased risk of gallbladder carcinoma. RAD52 is a crucial human deoxyribonucleic acid (DNA) repair gene involved in maintaining genomic stability and preventing tumor occurrence. PATIENT CONCERNS: A...
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