Association between Single-Nucleotide Polymorphism in MicroRNA Target Site of DDB2 and Risk of Hepatocellular Carcinoma in a Southern Chinese Population.

doi:10.1155/2020/8528747

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Article

Association between Single-Nucleotide Polymorphism in MicroRNA Target Site of DDB2 and Risk of Hepatocellular Carcinoma in a Southern Chinese Population.

BioMed research international - 1 Jan 2020

Qiu Moqin, Liu Yingchun, Zhou Zihan, Jiang Yanji, Lin Qiuling, Huo Rongrui, Liang Xiumei, Yu Xiangyuan, Zhou Xianguo, Yu Hongping

Abstract excerpt

Damage-specific DNA-binding protein 2 (DDB2) is a DNA repair protein mainly involved in nucleotide excision repair, which plays a pivotal role in maintaining genomic stability. In this study, we evaluated the association of single-nucleotide polymorphism (SNP) rs1050244 in miRNA target site of DDB2 gene with risk of hepatocellular carcinoma (HCC) among 1073 HCC patients and 1119 cancer-free controls in a southern...

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PMID: 32090112
DOI: 10.1155/2020/8528747
PMCID: PMC7031712

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