Article
Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells.
PloS one - 1 Jan 2014
Baysan Mehmet, Woolard Kevin, Bozdag Serdar, Riddick Gregory, Kotliarova Svetlana, Cam Margaret C, Belova Galina I, Ahn Susie, Zhang Wei, Song Hua, Walling Jennifer, Stevenson Holly, Meltzer Paul, Fine Howard A
Abstract excerpt
In vitro and in vivo models are widely used in cancer research. Characterizing the similarities and differences between a patient's tumor and corresponding in vitro and in vivo models is important for understanding the potential clinical relevance of experimental data generated with these models....
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