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Article

Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.

Apoptosis : an international journal on programmed cell death - 1 Jul 2014

Balogh András, Németh Mária, Koloszár Ibolya, Markó Lajos, Przybyl Lukasz, Jinno Kazushi, Szigeti Csilla, Heffer Marija, Gebhardt Matthias, Szeberényi József, Müller Dominik N, Sétáló György, Pap Marianna

Abstract excerpt

Endoplasmic reticulum (ER) stress plays an essential role in unfolded protein response induced apoptosis contributing to several pathological conditions. Glycogen synthase kinase-3β (GSK-3β) plays a central role in several apoptotic signaling, including ER stress, as the active form of GSK-3β induces apoptosis. The phosphorylation of cAMP responsive element (CRE) binding protein (CREB) Ser-133 (S133) residue is...

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Identifiers

PMID: 24722832
DOI: 10.1007/s10495-014-0986-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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