Article
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX.
Nature protocols - 1 May 2014
Schubert Mikkel, Ermini Luca, Der Sarkissian Clio, Jónsson Hákon, Ginolhac Aurélien, Schaefer Robert, Martin Michael D, Fernández Ruth, Kircher Martin, McCue Molly, Willerslev Eske, Orlando Ludovic
Abstract excerpt
Next-generation sequencing technologies have revolutionized the field of paleogenomics, allowing the reconstruction of complete ancient genomes and their comparison with modern references. However, this requires the processing of vast amounts of data and involves a large number of steps that use a variety of computational tools. Here we present PALEOMIX (http://geogenetics.ku.dk/publications/paleomix), a flexible...
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