SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese.

doi:10.1038/jhg.2012.11

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Article

SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese.

Journal of human genetics - 1 Apr 2012

Fan Yan-Hui, Song You-Qiang, Chan Danny, Takahashi Yohei, Ikegawa Shiro, Matsumoto Morio, Kou Ikuyo, Cheah Kathryn S E, Sham Pak, Cheung Kenneth M C, Luk Keith D K

Abstract excerpt

A study was conducted to validate the most significant single nucleotide polymorphism (SNP) from a genome-wide association study of Japanese adolescent idiopathic scoliosis (AIS) patients in an independent southern Chinese population. In total, 300 AIS patients fulfilled the clinical criteria and 788 controls with MRI scans of the spine were included in the replication study. We employed case-control analysis to...

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PMID: 22301463
DOI: 10.1038/jhg.2012.11

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LBX1

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